Efficient synthesis of cyclopentenones from enynyl acetates via tandem Au(I)-catalyzed 3,3-rearrangement and the Nazarov reaction

被引：334

作者：

Zhang, LM ^{[1
]}

Wang, SZ ^{[1
]}

机构：

[1] Univ Nevada, Dept Chem 216, Reno, NV 89557 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 05期

关键词：

D O I：

10.1021/ja057327q

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly efficient method for the synthesis of versatile cyclopentenones from readily available enynyl acetates via tandem Au(I)-catalyzed 3,3-rearrangement and the Nazarov reaction is developed. Significant substrate flexibility and excellent control of the double bond position in the cyclopentenone ring render this an attractive method for cyclopentenone synthesis. Copyright © 2006 American Chemical Society.

引用

页码：1442 / 1443

页数：2

共 27 条

[1] Highly efficient access to strained bicyclic ketals via gold-catalyzed cycloisomerization of bis-homopropargylic diols [J].