Tin-free radical chemistry: intramolecular addition of alkyl radicals to aldehydes and ketones

被引：56

作者：

Devin, P ^{[1
]}

Fensterbank, L ^{[1
]}

Malacria, M ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Chim Organ Synth, F-75252 Paris 05, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(99)01072-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The radical cyclization of several omega-iodoaldehydes and a ketone can be accomplished without the use of tributyltin hydride. Triethylborane in presence of oxygen or light from a sun lamp can serve as a radical initiator and terminator. In these conditions, a 5-exo-trig cyclization on an aldehyde is faster than on an alkene. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：5511 / 5514

页数：4

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