Enantioselective direct-addition of terminal alkynes to imines catalyzed by copper(I)pybox complex in water and in toluene

被引：492

作者：

Wei, CM ^{[1
]}

Li, CJ ^{[1
]}

机构：

[1] Tulane Univ, Dept Chem, New Orleans, LA 70118 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 20期

关键词：

D O I：

10.1021/ja026007t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Highly enantioselective direct alkyne-imine additions catalyzed by Cu(I)OTf and Evan's pybox ligands were developed in water and in toluene. The process is simple and provides a diverse range of propargylic amine in high ee and good yield. Copyright © 2002 American Chemical Society.

引用

页码：5638 / 5639

页数：2

共 27 条

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