Expeditious tandem-metathesis route to the AB-ring fragment of ciguatoxin

被引：67

作者：

Oguri, H

Sasaki, S

Oishi, T

Hirama, M ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Sendai, Miyagi 9808578, Japan

[2] Japan Sci & Technol Corp, CREST, Sendai, Miyagi 9808578, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 29期

关键词：

ciguatoxin; diastereoselective ring-closing metathesis; cross metathesis; umpolung of pi-allyl palladium;

D O I：

10.1016/S0040-4039(99)01017-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The AB-ring fragment of ciguatoxin was synthesized in ten steps from tri-O-benzyl-D-glucal based on a highly diastereoselective ring-closing metathesis and subsequent cross metathesis. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5405 / 5408

页数：4

共 37 条

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