Liquid chromatography-inductively coupled plasma mass spectrometry

被引:75
作者
Sutton, KL [1 ]
Caruso, JA [1 ]
机构
[1] Univ Cincinnati, Dept Chem, Cincinnati, OH 45221 USA
关键词
inductively coupled plasma mass spectrometry; interfaces; LC-MS; trace analysis;
D O I
10.1016/S0021-9673(99)00580-4
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The technique of coupling liquid chromatography to inductively coupled plasma mass spectrometry (ICP-MS) is reviewed. A brief introduction to the ICP-MS instrument is given as well as methods to couple the two analytical instruments together. The various types of LC that have been used with ICP-MS detection are discussed and advantages over traditional methods of detection are highlighted, such as the improvements in sensitivity and selectivity. Several applications that have been described in the literature are reviewed. An outlook for the future of LC-ICP-MS, particularly with regard to elemental speciation is given. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:243 / 258
页数:16
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