The target of acute stroke therapy and neuroprotective therapeutic approaches

被引：7

作者：

Fisher, M ^{[1
]}

机构：

[1] Univ Massachusetts, Med Ctr, Worcester, MA 01605 USA

来源：

REVISTA DE NEUROLOGIA | 1999年 / 29卷 / 06期

关键词：

cerebral ischemia; ischemic penumbra; neuroprotection; stroke; therapeutic window;

D O I：

10.33588/rn.2906.99174

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In this article we review the concept of ischemic penumbra and emphasize the potentially reversible aspect as a function of time, which is the basis of the concept of a therapeutic window. Also, we briefly consider the physiopathology of the ischemic cascade emphasizing the levels at which the different neuroprotector drugs under investigation have their effect.

引用

页码：536 / 544

页数：9

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