A helicase that gets Oskar's message across

被引:3
作者
Davis, I [1 ]
机构
[1] Univ Edinburgh, Wellcome Trust Ctr Cell Biol, Edinburgh EH9 3JR, Midlothian, Scotland
关键词
D O I
10.1038/ncb0404-285
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
Messenger RNA localization is a common way of targeting proteins to their site of function. This process is dependent on RNA signals that are interpreted by trans-acting factors. A putative RNA helicase and translational initiation factor is now shown to form a conserved complex, important for localization of oskar mRNA in Drosophila melanogaster and RNA surveillance in human cells.
引用
收藏
页码:285 / 287
页数:3
相关论文
共 14 条
[1]
[Anonymous], 2003, Nature Reviews Molecular Cell Biology
[2]
Recognition of a bicoid mRNA localization signal by a protein complex containing swallow, Nod, and RNA binding proteins [J].
Arn, EA ;
Cha, BJ ;
Theurkauf, WE ;
Macdonald, PM .
DEVELOPMENTAL CELL, 2003, 4 (01) :41-51
[3]
A function for kinesin I in the posterior transport of oskar mRNA and Staufen protein [J].
Brendza, RP ;
Serbus, LR ;
Duffy, JB ;
Saxton, WM .
SCIENCE, 2000, 289 (5487) :2120-2122
[4]
eIF4A3 is a novel component of the exon junction complex [J].
Chan, CC ;
Dostie, J ;
Diem, MD ;
Feng, WQ ;
Mann, M ;
Rappsilber, J ;
Dreyfuss, G .
RNA, 2004, 10 (02) :200-209
[5]
INDUCTION OF GERM-CELL FORMATION BY OSKAR [J].
EPHRUSSI, A ;
LEHMANN, R .
NATURE, 1992, 358 (6385) :387-392
[6]
Seeing is believing: The bicoid morphogen gradient matures [J].
Ephrussi, A ;
St Johnston, D .
CELL, 2004, 116 (02) :143-152
[7]
Nonsense-mediated mRNA decay in Drosophila:: at the intersection of the yeast and mammalian pathways [J].
Gatfield, D ;
Unterholzner, L ;
Ciccarelli, FD ;
Bork, P ;
Izaurralde, E .
EMBO JOURNAL, 2003, 22 (15) :3960-3970
[8]
mRNA localization: Message on the move [J].
Jansen, RP .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (04) :247-256
[9]
Drosophila gurken (TGFα) mRNA localizes as particles that move within the oocyte in two dynein-dependent steps [J].
MacDougall, N ;
Clark, A ;
MacDougall, E ;
Davis, I .
DEVELOPMENTAL CELL, 2003, 4 (03) :307-319
[10]
MRNA turnover [J].
Mitchell, P ;
Tollervey, D .
CURRENT OPINION IN CELL BIOLOGY, 2001, 13 (03) :320-325