Enzymatic protecting group techniques

被引：122

作者：

Kadereit, D

Waldmann, H

机构：

[1] Max Planck Inst Mol Physiol, Abt Chem Biol, D-44227 Dortmund, Germany

[2] Univ Karlsruhe, Inst Organ Chem, D-76128 Karlsruhe, Germany

[3] Univ Dortmund, Fachbereich 3, Dortmund, Germany

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 11期

关键词：

D O I：

10.1021/cr010146w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The techniques used for introducing and removal of enzymatic protecting groups in organic synthesis reactions were discussed. The removal of the groups using biocatalyzed transformations offered the opportunity to perform useful functional group interconversions with a high degree of selectivity. The study provided a basis for the the application of biocatalysts in the handling of protecting group problems in complex multistep synthesis.

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页码：3367 / 3396

页数：30

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