Parkinson's disease: an update on pathogenesis and treatment

被引：28

作者：

Foltynie, Tom ^{[1
,2
]}

Kahan, Joshua ^{[2
]}

机构：

[1] Natl Hosp Neurol & Neurosurg, Box 146,Queen Sq, London WC1N 3BG, England

[2] UCL Inst Neurol, Sobell Dept Motor Neurosci, London WC1N 3BG, England

来源：

JOURNAL OF NEUROLOGY | 2013年 / 260卷 / 05期

关键词：

Parkinson's disease; Pathogenesis; Treatment; Update; ALPHA-SYNUCLEIN; NEUROTROPHIC FACTOR; SUBSTANTIA-NIGRA; CONTROLLED-TRIAL; DOPAMINERGIC-NEURONS; RODENT MODELS; GENE-THERAPY; COMPLEX-I; GLUCOCEREBROSIDASE; BRAIN;

D O I：

10.1007/s00415-013-6915-1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The Parkinson's disease research field is a rapidly moving one, as many of the relevant processes underlying PD neurodegeneration are being deciphered, enabling novel approaches to treatment to be assessed both in the laboratory and in the clinic. This review aims to highlight the most relevant updates in the PD field, with emphasis on research that may help lead towards an improvement in the treatment of this condition.

引用

页码：1433 / 1440

页数：8

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