Monte Carlo simulation of an optical coherence tomography signal in homogeneous turbid media

被引:154
作者
Yao, G [1 ]
Wang, LHV [1 ]
机构
[1] Texas A&M Univ, Biomed Engn Program, Opt Imaging Lab, College Stn, TX 77843 USA
关键词
D O I
10.1088/0031-9155/44/9/316
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The Monte Carlo technique with angle biasing is used to simulate the optical coherence tomography (OCT) signal from homogeneous turbid media. The OCT signal is divided into two categories: one is from a target imaging layer in the medium (Class I); the other is from the rest of the medium (Class II). These two classes of signal are very different in their spatial distributions, angular distributions and the numbers of experienced scattering events. Multiply scattered light contributes to the Class I signal as well as the Class II signal. The average number of scattering events increases linearly with the probing depth. The Class II signal decays much more slowly than the Class I signal whose decay constant is close to the total attenuation coefficient of the turbid medium. The effect of the optical properties of the medium on the Class I signal decay is studied.
引用
收藏
页码:2307 / 2320
页数:14
相关论文
共 12 条
[1]   ANISOTROPIC ANGLE BIASING OF PHOTONS [J].
HENDRICKS, JS ;
CARTER, LL .
NUCLEAR SCIENCE AND ENGINEERING, 1985, 89 (02) :118-130
[2]   OPTICAL COHERENCE TOMOGRAPHY [J].
HUANG, D ;
SWANSON, EA ;
LIN, CP ;
SCHUMAN, JS ;
STINSON, WG ;
CHANG, W ;
HEE, MR ;
FLOTTE, T ;
GREGORY, K ;
PULIAFITO, CA ;
FUJIMOTO, JG .
SCIENCE, 1991, 254 (5035) :1178-1181
[3]   LOW-COHERENCE OPTICAL TOMOGRAPHY IN TURBID TISSUE - THEORETICAL-ANALYSIS [J].
PAN, YT ;
BIRNGRUBER, R ;
ROSPERICH, J ;
ENGELHARDT, R .
APPLIED OPTICS, 1995, 34 (28) :6564-6574
[4]  
PULIAFITO CA, 1995, OPHTHALMOLOGY, V102, P217
[5]   MEASUREMENT OF OPTICAL-PROPERTIES OF BIOLOGICAL TISSUES BY LOW-COHERENCE REFLECTOMETRY [J].
SCHMITT, JM ;
KNUTTEL, A ;
BONNER, RF .
APPLIED OPTICS, 1993, 32 (30) :6032-6042
[6]   Model of optical coherence tomography of heterogeneous tissue [J].
Schmitt, JM ;
Knuttel, A .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1997, 14 (06) :1231-1242
[7]   Efficient monte carlo simulation of confocal microscopy in biological tissue [J].
Schmitt, JM ;
BenLetaief, K .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1996, 13 (05) :952-961
[8]   ANTENNA PROPERTIES OF OPTICAL HETERODYNE RECEIVERS [J].
SIEGMAN, AE .
APPLIED OPTICS, 1966, 5 (10) :1588-&
[9]   Signal attenuation and localization in optical coherence tomography studied by Monte Carlo simulation [J].
Smithies, DJ ;
Lindmo, T ;
Chen, ZP ;
Nelson, JS ;
Milner, TE .
PHYSICS IN MEDICINE AND BIOLOGY, 1998, 43 (10) :3025-3044
[10]   MEASUREMENT OF RAYLEIGH BACKSCATTERING AT 1.55 MU-M WITH 32 MU-M SPATIAL-RESOLUTION [J].
SORIN, WV ;
BANEY, DM .
IEEE PHOTONICS TECHNOLOGY LETTERS, 1992, 4 (04) :374-376