Novel protein phosphatases in yeast -: An update

被引：35

作者：

Ariño, J ^{[1
]}

机构：

[1] Univ Autonoma Barcelona, Fac Vet, Dept Biochem & Mol Biol, E-08193 Barcelona, Spain

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 2002年 / 269卷 / 04期

关键词：

Ser/Thr protein phosphatases; cell cycle; cell integrity; cation tolerance; protein synthesis; yeast;

D O I：

10.1046/j.0014-2956.2002.02753.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During the last decade several novel yeast genes encoding proteins related to the PPP family of Ser/Thr protein phosphatases have been discovered and their functional characterization initiated. Most of these novel phosphatases display intriguing structural features and/or are involved in a number of important functions, such as cell cycle regulation, protein synthesis and maintenance of cellular integrity. While in some cases these genes appear to be restricted to fungi, in others similar proteins can be found in higher eukaryotes. This review will summarize the latest advances in our understanding about how these phosphatases are regulated and fulfil their functions in the yeast cell.

引用

页码：1072 / 1077

页数：6

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