Protein phosphatase 5 in signal transduction

被引:110
作者
Chinkers, M [1 ]
机构
[1] Univ S Alabama, Dept Pharmacol, Mobile, AL 36688 USA
关键词
D O I
10.1016/S1043-2760(00)00335-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Protein phosphatase 5 (PP5) possesses unique biochemical properties, which include its tetratricopeptide repeat (TPR) targeting/regulatory domain and its ability to he activated by lipids. PP5 has been studied as a paradigm for TPR protein structure and function. Roles for PP5 in signal transduction are emerging:from cell cycle regulation and signaling by nuclear receptors, to possible regulation of membrane receptors and ion channels.
引用
收藏
页码:28 / 32
页数:5
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