Carbon-fiber microelectrodes modified with 4-sulfobenzene have increased sensitivity and selectivity for catecholamines

被引：61

作者：

Hermans, A ^{[1
]}

Seipel, AT ^{[1
]}

Miller, CE ^{[1
]}

Wightman, RM ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

LANGMUIR | 2006年 / 22卷 / 05期

关键词：

D O I：

10.1021/la053032e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Elliptical and cylindrical geometries of carbon-fiber microelectrodes were modified by covalent attachment of 4-sulfobenzenediazonium tetrafluoroborate following its electroreduction. Elliptical electrodes fabricated from Thornel P-55 carbon fibers show the highest amount of 4-sulfobenzene attached to the electrode. Fast-scan cyclic voltammetry was used to compare the response to dopamine and other neurochemicals at these modified carbon-fiber microelectrodes. The grafted layer causes an increased sensitivity to dopamine and other positively charged analytes that is due to increased adsorption of analyte in the grafted layer. However, this layer remains permeable to negatively charged compounds.

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页码：1964 / 1969

页数：6

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