Transcranial Magnetic Stimulation in Child Neurology: Current and Future Directions

被引:80
作者
Frye, Richard E. [1 ]
Rotenberg, Alexander [2 ,3 ,4 ]
Ousley, Molliann [5 ]
Pascual-Leone, Alvaro [3 ,4 ,6 ]
机构
[1] Univ Texas Hlth Sci Ctr Houston, Dept Pediat, Div Child Neurol, Houston, TX 77030 USA
[2] Childrens Hosp Boston, Dept Neurol, Boston, MA USA
[3] Beth Israel Deaconess Med Ctr, Dept Neurol, Berenson Allen Ctr Noninvas Brain Stimulat, Boston, MA 02215 USA
[4] Harvard Univ, Sch Med, Boston, MA USA
[5] Univ Florida, Gainesville, FL USA
[6] Univ Autonoma Barcelona, Inst Guttmann Neurorehabilitacio, Barcelona, Spain
关键词
transcranial magnetic stimulation; corticospinal pathway maturation; cortical reorganization; corticospinal abnormalities; cortical excitability; cortical plasticity;
D O I
10.1177/0883073807307972
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Transcranial magnetic Stimulation (TMS) is a method for focal brain stimulation based on the principle of electromagnetic induction, where small intracranial electric currents are generated by a powerful, rapidly changing extracranial magnetic field. Over the past 2 decades TMS has shown promise in the diagnosis, monitoring, and treatment of neurological and psychiatric disease in adults, but has been used on a more limited basis in children. We reviewed the literature to identify potential diagnostic and therapeutic applications of TMS in child neurology and also its safety in pediatrics. Although TMS has not been associated with any serious side effects in children and appears to be well tolerated, general safety guidelines should be established. The potential for applications of TMS in child neurology and psychiatry is significant. Given its excellent safety profile and possible therapeutic effect, this technique should develop as an important tool in pediatric neurology over the next decade.
引用
收藏
页码:79 / 96
页数:18
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