Development of novel Lewis acid catalysts for selective organic reactions in aqueous media

被引:799
作者
Kobayashi, S [1 ]
Manabe, K [1 ]
机构
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
关键词
D O I
10.1021/ar000145a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
New types of Lewis acids as water-compatible catalysts have been developed. Various metal salts were found to work as Lewis acid catalysts in aqueous media, and catalytic asymmetric aldol reactions in such media have been attained. Furthermore, Lewis acid-surfactant combined catalysts, which can be used for reactions in water without using any organic cosolvents, have been also developed. These investigations will contribute to reducing the use of harmful organic solvents and to develop efficient catalytic systems which cannot be realized in conventional organic solvents.
引用
收藏
页码:209 / 217
页数:9
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共 66 条
  • [11] Fringuelli F, 2001, EUR J ORG CHEM, V2001, P439, DOI 10.1002/1099-0690(200102)2001:3<439::AID-EJOC439>3.0.CO
  • [12] 2-B
  • [13] Lewis-acid catalyzed organic reactions in water.: The case of AlCl3, TiCl4, and SnCl4 believed to be unusable in aqueous medium
    Fringuelli, F
    Pizzo, F
    Vaccaro, L
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (13) : 4719 - 4722
  • [14] Grieco P.A., 1998, Organic synthesis in water
  • [15] HAY RW, 1987, COMPREHENSIVE COORDI, V6, P411
  • [16] Holland PM, 1992, ACS Symposium Series
  • [17] Ytterbium triflate catalyzed Michael additions of beta-ketoesters in water
    Keller, E
    Feringa, BL
    [J]. TETRAHEDRON LETTERS, 1996, 37 (11) : 1879 - 1882
  • [18] Kim B. M., 1991, COMPREHENSIVE ORGANI, V2, P239, DOI DOI 10.1016/B978-0-08-052349-1.00029-9
  • [19] KOBAYASHI S, 1994, SYNLETT, P689
  • [20] Catalytic asymmetric aldol reactions in water using a chiral Lewis-acid-surfactant-combined catalyst
    Kobayashi, S
    Mori, Y
    Nagayama, S
    Manabe, K
    [J]. GREEN CHEMISTRY, 1999, 1 (04) : 175 - 177