B-mode enhancement at phase-inversion US with air-based microbubble contrast agent: Initial experience in humans

被引：72

作者：

Albrecht, T

Hoffmann, CW

Schettler, S

Overberg, A

Ilg, M

von Behren, PL

Bauer, A

Wolf, KJ

机构：

[1] Free Univ Berlin, Klinikum Benjamin Franklin, Dept Radiol & Nucl Med, D-12200 Berlin, Germany

[2] Siemens US Grp, Issaquah, WA USA

[3] Schering, Dept Clin Dev, Berlin, Germany

来源：

RADIOLOGY | 2000年 / 216卷 / 01期

关键词：

ultrasound; (US); contrast media;

D O I：

10.1148/radiology.216.1.r00jl27273

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Pulse- or phase-inversion ultrasonography (US) sums the signals returned from two 180 degrees ultrasound pulses. Linear scattering from tissue results in a signal void while nonlinear signals from microbubbles stand out. The technique was applied with a US contrast agent in 39 human subjects. B-mode enhancement of vessels and organ parenchyma was seen in all cases. Enhancement occurred from flowing and stationary microbubbles. The flow-independent enhancement of normal and abnormal tissue represents a major advance in contrast material-enhanced US with many potential applications especially in tumor imaging.

引用

收藏

页码：273 / 278

页数：6

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