Metal-catalyzed [2+2+1] cycloadditions of 1,3-dienes, allenes, and CO

被引：56

作者：

Wender, PA ^{[1
]}

Croatt, MP ^{[1
]}

Deschamps, NM ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 15期

关键词：

allenes; cycloaddition; dienes; Pauson-Khand reaction; rhodium;

D O I：

10.1002/anie.200600300

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Closing the circle: RhI-catalyzed [2+2+1] cycloadditions are achieved under mild reaction conditions and in good to excellent yields with catalyst loading as low as 0.1 mol%. The diene-allenes react selectively with the proximal double bonds of the allene and diene units, thus allowing for a variety of substitutions. DCE = 1,2-dichloroethane, TFE = 2,2,2-trifluoroethanol, Ts = tosyl. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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页码：2459 / 2462

页数：4

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