Rhodium(I)-catalyzed ene-allene carbocyclization strategy for the formation of azepines and oxepines

被引：52

作者：

Brummond, KM ^{[1
]}

Chen, HF ^{[1
]}

Mitasev, B ^{[1
]}

Casarez, AD ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 13期

关键词：

D O I：

10.1021/ol049390a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel strategy for the preparation of seven-membered heterocyclic compounds has been realized. Treatment of ene-allene 1 with a catalytic quantity of rhodium biscarbonyl chloride dimer affords the cyclization product 2 in moderate to high yields. The scope and limitations of this new method are currently under investigation, and the results obtained to date are discussed within.

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页码：2161 / 2163

页数：3

相关论文

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