An efficient route to alkyl chlorides from alcohols using the complex TCT/DMF

被引：148

作者：

De Luca, L ^{[1
]}

Giacomelli, G ^{[1
]}

Porcheddu, A ^{[1
]}

机构：

[1] Univ Sassari, Dipartimento Chim, I-07100 Sassari, Italy

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 04期

关键词：

D O I：

10.1021/ol017168p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient conversion of alcohols and beta\-amino alcohols to the corresponding chlorides (and bromides) can be carried out at room temperature in methylene chloride, using 2,4,6-trichloro[1,3,5]triazine and N,N-dimethyl formamide. This procedure can also be applied to optically active carbinols.

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页码：553 / 555

页数：3

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