A simple preparation of ketones.: N-protected α-amino ketones from α-amino acids

被引：65

作者：

De Luca, L ^{[1
]}

Giacomelli, G ^{[1
]}

Porcheddu, A ^{[1
]}

机构：

[1] Univ Studi Sassari, Dipartimento Chim, I-07100 Sassari, Italy

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 10期

关键词：

D O I：

10.1021/ol015840c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carboxylic acids and amino acids are readily converted, under mild conditions, into the corresponding activated esters, which are reacted with Grignard/Cul reagent to give the corresponding ketones in nearly quantitative yields. The compounds were recovered substantially pure from the reaction mixtures.

引用

页码：1519 / 1521

页数：3

共 15 条

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