Evidence-Based Point-of-Care Diagnostics: Current Status and Emerging Technologies

被引：76

作者：

Chan, Cangel Pui Yee ^{[1
]}

Mak, Wing Cheung ^{[3
]}

Cheung, Kwan Yee ^{[4
]}

Sin, King Keung ^{[5
]}

Yu, Cheuk Man ^{[2
]}

Rainer, Timothy H. ^{[1
]}

Renneberg, Reinhard ^{[5
]}

机构：

[1] Chinese Univ Hong Kong, Accident & Emergency Med Acad Unit, Shatin, Hong Kong, Peoples R China

[2] Chinese Univ Hong Kong, Div Cardiol, Dept Med & Therapeut, Prince Wales Hosp, Shatin, Hong Kong, Peoples R China

[3] Linkoping Univ, Dept Phys Chem & Biol, Biosensors & Bioelect Ctr, S-58183 Linkoping, Sweden

[4] Linkoping Univ, Dept Clin & Expt Med, Integrat Regenerat Med Ctr, S-58183 Linkoping, Sweden

[5] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

来源：

ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 6 | 2013年 / 6卷

关键词：

acute coronary syndrome; heart failure; human immunodeficiency virus; microfluidics; POC; tuberculosis; DECOMPENSATED HEART-FAILURE; LAB-ON-PAPER; MYCOBACTERIUM-TUBERCULOSIS; EMERGENCY-DEPARTMENT; MICROFLUIDIC DEVICES; MYOCARDIAL-INFARCTION; NATRIURETIC PEPTIDE; CARDIAC BIOMARKERS; OPTICAL-DETECTION; LIQUID-CRYSTALS;

D O I：

10.1146/annurev-anchem-062012-092641

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Point-of-care (POC) diagnostics brings tests nearer to the site of patient care. The turnaround time is short, and minimal manual interference enables quick clinical management decisions. Growth in POC diagnostics is being continuously fueled by the global burden of cardiovascular and infectious diseases. Early diagnosis and rapid initiation of treatment are crucial in the management of such patients. This review provides the rationale for the use of POC tests in acute coronary syndrome, heart failure, human immunodeficiency virus, and tuberculosis. We also consider emerging technologies that are based on advanced nanomaterials and microfluidics, improved assay sensitivity, miniaturization in device design, reduced costs, and high-throughput multiplex detection, all of which may shape the future development of POC diagnostics.

引用

页码：191 / 211

页数：21

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