Clay: New Opportunities for Tissue Regeneration and Biomaterial Design

被引:325
作者
Dawson, Jonathan I. [1 ]
Oreffo, Richard O. C. [1 ]
机构
[1] Univ Southampton, Inst Dev Sci, Southampton SO16 6YD, Hants, England
基金
英国生物技术与生命科学研究理事会;
关键词
clay materials; nanoparticles; nanocomposites; drug delivery; tissue regeneration; DRUG-RELEASE BEHAVIOR; CROSS-LINKED PEO; NANOCOMPOSITE HYDROGELS; IN-VITRO; MECHANICAL-PROPERTIES; OSTEOGENIC DIFFERENTIATION; MOLECULAR CHARACTERISTICS; SILICATE NANOCOMPOSITES; POLY(ETHYLENE GLYCOL); MODIFIED NANOCLAYS;
D O I
10.1002/adma.201301034
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers, and cells are examined, focusing on the implications for tissue engineering and regenerative strategies. Pioneering studies demonstrating the utility of clay for drug-delivery and scaffold design are reviewed and areas for future research and development highlighted.
引用
收藏
页码:4069 / 4086
页数:18
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