Monitoring teriparatide-associated changes in vertebral microstructure by high-resolution CT in vivo:: Results from the EUROFORS study

被引：123

作者：

Graeff, Christian

Timm, Wolfram

Nickelsen, Thomas N.

Farrerons, Jordi

Marin, Fernando

Barker, Clare

Glueer, Claus C.

机构：

[1] Univ Klinikum Schleswig Holstein, Radiol Diagnost Klin, Lubeck, Germany

[2] Eli Lilly & Co, Windlesham, Surrey, England

[3] Hosp Santa Creu & Sant Pau, E-08025 Barcelona, Spain

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2007年 / 22卷 / 09期

关键词：

osteoporosis; teriparatide; bone microstructure; CT; BMD;

D O I：

10.1359/jbmr.070603

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We introduce a method for microstructural analysis of vertebral trabecular bone in vivo based on HRCT. When applied to monitor teriparatide treatment, changes in structural variables exceeded and were partially independent of changes in volumetric BMD.

引用

收藏

页码：1426 / 1433

页数：8

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