Capillary filling of miniaturized sources for electrospray mass spectrometry

被引:8
作者
Arscott, Steve
Gaudet, Matthieu
Brinkmann, Martin
Ashcroft, Alison E.
Blossey, Ralf
机构
[1] CNRS, UMR 8520, IEMN, F-59652 Villeneuve Dascq, France
[2] Interdisciplinary Res Inst, IEMN, Biol Nanosyst Grp, F-59652 Villeneuve Dascq, France
[3] Max Planck Inst Dynam & Self Org, D-37073 Gottingen, Germany
[4] Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England
关键词
D O I
10.1088/0953-8984/18/18/S13
中图分类号
O469 [凝聚态物理学];
学科分类号
070205 ;
摘要
Capillary slot-based emitter tips are a novel tool for use in electrospray ionization-mass spectrometry of large biomolecules. We have performed a combined theoretical and experimental study of capillary filling in micron-sized slots with the aim of developing a rational design procedure for miniaturized electrospray sources, ultimately enabling the integration of ESI into laboratory-on-a-chip devices.
引用
收藏
页码:S677 / S690
页数:14
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