Facile one-pot synthesis of luminescent, water-soluble, and biocompatible glutathione-coated CdTe nanocrystals

被引：207

作者：

Qian, HF ^{[1
]}

Dong, CQ ^{[1
]}

Weng, JF ^{[1
]}

Ren, JC ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Coll Chem & Chem Engn, Shanghai 200240, Peoples R China

来源：

SMALL | 2006年 / 2卷 / 06期

关键词：

luminescence; nanocrystals; nanotechnology; quantum dots; semiconductors;

D O I：

10.1002/smll.200500530

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile strategy to synthesize highly luminescent, water-soluble, and biocompatible CdTe nanocrystals using a biomolecule tripeptide glutathione (GSH) as a stabilizer was analyzed. The GSH-coated CdTe nanocrystals were covalently coupled to the anti-von Willebrand factor antibody (anti-vWF) for the imaging of human umbilical vein endothelial (HUVE) cells. It was found that the GSH-coated nanocrystals have up to 62% quantum yield and their size-dependent emission ranged from 480 to 650 nm. Fluorescence correlation spectroscopy (FCS) showed that the CdTe nanocrystals possessed a good crystalline structure and excellent luminescence properties. It was also found that the nanocrystals have good water solubility and biocompatibility, and are suitable for cell imaging and biolabeling.

引用

页码：747 / 751

页数：5

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