Total synthesis of aspercyclide C

被引：58

作者：

Fürstner, A ^{[1
]}

Müller, C ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 44期

关键词：

D O I：

10.1039/b512877c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first total synthesis of (+)-aspercyclide C (1) is reported using a kinetically controlled RCM reaction to form the 11-membered, unsaturated lactone ring of this bioactive diaryl ether macrolide.

引用

页码：5583 / 5585

页数：3

共 54 条

[1] Total syntheses of amphidinolide T1, T3, T4, and T5 [J].

Aïssa, C ;

Riveiros, R ;

Ragot, J ;

Fürstner, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (50) :15512-15520

[2] Concise synthesis of azacycloundecenes using ring-closing metathesis (RCM) [J].

Arisawa, M ;

Kato, C ;

Kaneko, H ;

Nishida, A ;

Nakagawa, M .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2000, (12) :1873-1876

[3] A formal total synthesis of eleutherobin through an unprecedented kinetically controlled ring-closing-metathesis reaction of a densely functionalized diene [J].

Castoldi, D ;

Caggiano, L ;

Panigada, L ;

Sharon, O ;

Costa, AM ;

Gennari, C .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (04) :588-591

[4] Metathesis-based synthesis of jasmonate and homojasmonate lactones, candidates for extracellular quorum sensing molecules in Candida albicans [J].

Cho, SC ;

Dussault, PH ;

Lisec, AD ;

Jensen, EC ;

Nickerson, KW .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1999, (02) :193-196

[5]

Cossy J, 2002, SYNTHESIS-STUTTGART, P951

[6] Ring-closing metathesis in the synthesis of large and medium-sized oxacycles.: Application to the synthesis of polyoxygenated macrocycles [J].

Delgado, M ;

Martín, JD .

JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (13) :4798-4816

[7] Intramolecular silicon-assisted cross-coupling reactions:: General synthesis of medium-sized rings containing a 1,3-cis-cis diene unit [J].

Denmark, SE ;

Yang, SM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (10) :2102-2103

[8] Synthesis of cyclic sulfamoyl carbamates and ureas via ring-closing metathesis [J].

Dougherty, JM ;

Jiménez, M ;

Hanson, PR .

TETRAHEDRON, 2005, 61 (26) :6218-6230

[9] PARA-ANISYL GROUP - A VERSATILE PROTECTING GROUP FOR PRIMARY ALCOHOLS [J].

FUKUYAMA, T ;

LAIRD, AA ;

HOTCHKISS, LM .

TETRAHEDRON LETTERS, 1985, 26 (51) :6291-6292

[10] Concise and practical synthesis of latrunculin A by ring-closing enyne-yne metathesis [J].

Fürstner, A ;

Turet, L .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (22) :3462-3466

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