Salt concentration-induced dehybridisation of DNA-gold nanoparticle conjugate assemblies for diagnostic applications

被引：28

作者：

Oh, Ju-Hwan

Lee, Jae-Seung ^{[1
]}

机构：

[1] Korea Univ, Dept Mat Sci & Engn, Seoul 136713, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 34期

关键词：

COLORIMETRIC DETECTION; TEMPERATURE; ASSAY; IONS; HG2+;

D O I：

10.1039/c0cc01488e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present the cooperative dehybridisation of DNA-gold nanoparticle conjugate (DNA-AuNP) assemblies induced by reduced salt concentration ([salt]), which can be precisely controlled by various conditions. The detection of Ag(+) based upon the [salt]-induced dehybridisation of DNA-AuNP assemblies is five times more sensitive than that achieved under conventional thermal melting conditions.

引用

收藏

页码：6382 / 6384

页数：3

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