Bio-bar-code dendrimer-like DNA as signal amplifier for cancerous cells assay using ruthenium nanoparticle-based ultrasensitive chemiluminescence detection

被引：43

作者：

Bi, Sai ^{[1
]}

Hao, Shuangyuan ^{[1
]}

Li, Li ^{[1
]}

Zhang, Shusheng ^{[1
]}

机构：

[1] Qingdao Univ Sci & Technol, Key Lab Ecochem Engn, Minist Educ, Coll Chem & Mol Engn, Qingdao 266042, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 33期

基金：

中国国家自然科学基金;

关键词：

FLUORESCENCE NANOBARCODES; DELIVERY; POLYMER;

D O I：

10.1039/c0cc01409e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bio-bar-code dendrimer-like DNA (bbc-DL-DNA) is employed as a label for the amplification assay of cancer cells in combination with the newly explored chemiluminescence (CL) system of luminol-H(2)O(2)-Ru(3+) and specificity of structure-switching aptamers selected by cell-based SELEX.

引用

页码：6093 / 6095

页数：3

共 28 条

[11] Dendrimer/DNA complexes encapsulated functional biodegradable polymer for substrate-mediated gene delivery [J].

Fu, Hui-Li ;

Cheng, Si-Xue ;

Zhang, Xian-Zheng ;

Zhuo, Ren-Xi .

JOURNAL OF GENE MEDICINE, 2008, 10 (12) :1334-1342

[12] Nanopore DNA sensors based on dendrimer-modified nanopipettes [J].

Fu, Yaqin ;

Tokuhisa, Hideo ;

Baker, Lane A. .

CHEMICAL COMMUNICATIONS, 2009, (32) :4877-4879

[13] Selective Inhibition of Human Brain Tumor Cells through Multifunctional Quantum-Dot-Based siRNA Delivery [J].

Jung, Jongjin ;

Solanki, Aniruddh ;

Memoli, Kevin A. ;

Kamei, Ken-ichiro ;

Kim, Hiyun ;

Drahl, Michael A. ;

Williams, Lawrence J. ;

Tseng, Hsian-Rong ;

Lee, KiBum .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (01) :103-107

[14] Designing dendrimers for biological applications [J].

Lee, CC ;

MacKay, JA ;

Fréchet, JMJ ;

Szoka, FC .

NATURE BIOTECHNOLOGY, 2005, 23 (12) :1517-1526

[15] Multiplexed detection of pathogen DNA with DNA-based fluorescence nanobarcodes [J].

Li, YG ;

Cu, YTH ;

Luo, D .

NATURE BIOTECHNOLOGY, 2005, 23 (07) :885-889

[16] Controlled assembly of dendrimer-like DNA [J].

Li, YG ;

Tseng, YD ;

Kwon, SY ;

D'Espaux, L ;

Bunch, JS ;

Mceuen, PL ;

Luo, D .

NATURE MATERIALS, 2004, 3 (01) :38-42

[17] Multiplexed, particle-based detection of DNA using flow cytometry with 3DNA dendrimers for signal amplification [J].

Lowe, M ;

Spiro, A ;

Zhang, YZ ;

Getts, R .

CYTOMETRY PART A, 2004, 60A (02) :135-144

[18] Bimetallic dendrimer-encapsulated nanoparticles as catalysts: a review of the research advances [J].

Peng, Xiaohong ;

Pan, Qinmin ;

Rempel, Garry L. .

CHEMICAL SOCIETY REVIEWS, 2008, 37 (08) :1619-1628

[19]

Rabe KS, 2009, NAT MATER, V8, P370, DOI 10.1038/nmat2434

[20] Aptamer-conjugated nanoparticles for the collection and detection of multiple cancer cells [J].

Smith, Joshua E. ;

Medley, Colin D. ;

Tang, Zhiwen ;

Shangguan, Dihua ;

Lofton, Charles ;

Tan, Weihong .

ANALYTICAL CHEMISTRY, 2007, 79 (08) :3075-3082

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