Optimal frequencies for magnetic acceleration of cytochrome oxidase and Na,K-ATPase reactions

被引：31

作者：

Blank, M ^{[1
]}

Soo, L ^{[1
]}

机构：

[1] Columbia Univ, Dept Physiol & Cellular Biophys, New York, NY 10032 USA

来源：

BIOELECTROCHEMISTRY | 2001年 / 53卷 / 02期

关键词：

magnetic fields; electromagnetic fields; cytochrome oxidase; Na; K-ATPase; electron transport; frequency dependence;

D O I：

10.1016/S0302-4598(00)00128-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Low frequency magnetic fields increase the activity of the membrane enzymes, Na,K-ATPase and cytochrome oxidase, and the increased activity varies with frequency. Optimal frequencies for increases in the reaction rate constant of cytochrome oxidase and in the rate of splitting of ATP by Na,K-ATPase differ by an order of magnitude, and are in the ranges of the turnover numbers of the respective enzyme reactions. The two frequency dependence curves are similar in that the slope of the low frequency portion is about 10 times greater than the slope of the high frequency portion. The greater slope indicates greater ability to adjust quickly in the low frequency range, which may be significant for optimal biological control of activity. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：171 / 174

页数：4

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