Antitubercular constituents from the stem wood of Cinnamomum kotoense

被引：53

作者：

Chen, FC

Peng, CF

Tsai, IL

Chen, IS ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Coll Pharm, Grad Inst Nat Prod, Kaohsiung 807, Taiwan

[2] Kaohsiung Med Univ, Fac Biomed Lab Sci, Kaohsiung 807, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 09期

关键词：

D O I：

10.1021/np0580210

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Five new compounds, kotolactone A (1), kotolactone B (2), secokotomolide (3), kotodiol (4), and 2-acetyl-dodecylfuran (5), and 36 known compounds have been isolated from the stem wood of Cinnamomum 5 kotoense. The structures of these new compounds were determined by means of spectroscopic analysis. The known butanolides, isoobtusilactone A (6) and lincomolide B (7), showed in vitro antitubercular activities with MIC values of 22.48 and 10.16 mu M, respectively, against Mycobacterium tuberculosis 90221387.

引用

页码：1318 / 1323

页数：6

共 41 条

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