Identification of bismuth-thiolate-carboxylate clusters by electrospray ionization mass spectrometry

被引：16

作者：

Phillips, Heather A. ^{[1
]}

Burford, Neil ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4J3, Canada

来源：

INORGANIC CHEMISTRY | 2008年 / 47卷 / 07期

关键词：

D O I：

10.1021/ic701657r

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The known thermal and hydrolytic stability of bismuth-sulfur bonds indicates that biological targets for bismuth likely involve thiol or thiolate functionalities, such as in L-cysteine. Complexes of bismuth with cysteine or other thiol-carboxylic acid ligands have been isolated and characterized providing a preliminary view of the potential participation of these functional groups in the biochemical mechanisms involving bismuth. A broader assessment of bismuth-thiolate interactions has been possible using electrospray ionization mass spectrometry (ESI-MS). A wide range of complexes has been observed containing mercaptosuccinic acid, 2-mercaptopropionic acid, 3-mercaptopropionic acid, and/or 2-amino-3-mercaptopropionic acid (cysteine). The identification of various multibismuth multiligand cluster ions defines new chemistry for bismuth.

引用

页码：2428 / 2441

页数：14

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