A model for harmonizing flow cytometry in clinical trials

被引：115

作者：

Maecker, Holden T. ^{[1
]}

McCoy, J. Philip, Jr. ^{[2
]}

机构：

[1] Stanford Univ, Inst Immun Transplantat & Infect, Stanford, CA 94305 USA

[2] NHLBI, NIH, Bethesda, MD 20892 USA

来源：

NATURE IMMUNOLOGY | 2010年 / 11卷 / 11期

关键词：

FICOLL-HYPAQUE SEPARATION; BLOOD MONONUCLEAR-CELLS; WHOLE-BLOOD; T-CELLS; LYSIS TECHNIQUE; NORMAL ADULTS; ASSAYS; CRYOPRESERVATION; ANTICOAGULANT; INFORMATION;

D O I：

10.1038/ni1110-975

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Complexities in sample handling, instrument setup and data analysis are barriers to the effective use of flow cytometry to monitor immunological parameters in clinical trials. The novel use of a central laboratory may help mitigate these issues.

引用

页码：975 / 978

页数：4

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