Study of copper(I) catalysts for the synthesis of carbanucleosides via azide-alkyne 1,3-dipolar cycloaddition

被引：70

作者：

Broggi, Julie ^{[1
]}

Diez-Gonzalez, Silvia ^{[2
]}

Petersen, Jeffrey L. ^{[3
]}

Berteina-Raboin, Sabine ^{[1
]}

Nolan, Steven P. ^{[2
]}

Agrofoglio, Luigi A. ^{[1
]}

机构：

[1] Univ Orleans, Inst Chim Minerale & Analyt, UMR 6005, F-45067 Orleans, France

[2] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[3] W Virginia Univ, C Eugene Bennet Dept Chem, Morgantown, WV 26506 USA

来源：

SYNTHESIS-STUTTGART | 2008年 / 01期

关键词：

copper(I) catalysts; Huisgen 1,3-dipolar cycloaddition; carbanucleosides; N-heterocyclic carbenes;

D O I：

10.1055/s-2007-990943

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The activity of three copper(I)-based catalytic systems in the preparation of various 1,2,3 -triazolyl-carbanucleosides via the Huisgen azide-alkyne 1,3-dipolar cycloaddition is presented. The influence of the alkyne substituent, solvent, and heating mode were studied. The preparation of [1,2-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene]bromocopper [(IMes)CuBr] is discussed.

引用

页码：141 / 148

页数：8

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