Copper-catalyzed aerobic oxidative amidation of terminal alkynes: Efficient synthesis of ynamides

被引：428

作者：

Hamada, Tetsuya ^{[1
]}

Ye, Xuan ^{[1
]}

Stahl, Shannon S. ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 03期

关键词：

D O I：

10.1021/ja077406x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A copper-catalyzed method for the preparation of ynamides has been identified that proceeds via aerobic oxidative coupling of terminal alkynes with various nitrogen nucleophiles, including cyclic carbamates, amides and ureas, and N-alkyl-arylsulfonamides and indoles.

引用

页码：833 / +

页数：4

共 56 条

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