Palladium(0)-mediated synthesis of acetylated unsaturated 1,4-disaccharides

被引：13

作者：

Frappa, I

Kryczka, B

Lhoste, P

Porwanski, S

Sinou, D

Zawisza, A

机构：

[1] Univ Lyon 1, CPE Lyon, CNRS, Lab Synthese Asymetr, F-69622 Villeurbanne, France

[2] Univ Lodz, Inst Organ & Appl Chem, PL-90136 Lodz, Poland

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1998年 / 17卷 / 07期

关键词：

D O I：

10.1080/07328309808001888

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Alkylation of ethyl 6-O-tert-butyldiphenylsilyl-4-O-methoxycarbonyl-2,3-dideoxy alpha-D-erythro-hex-2-enopyranoside (1) with various peracetylated 1-hydroxy sugars in the presence of a catalytic amount of palladium(0) gave the corresponding unsaturated 1,4-disaccharides and trisaccharides. In all cases the reaction is regio- and stereospecific according to the unsaturated moiety, alkylation occuring only at C-4 of the unsaturated carbohydrate, with overall retention of configuration.

引用

页码：1117 / 1130

页数：14

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[21] SYNTHESIS OF GLYCOPEPTIDES, PARTIAL STRUCTURES OF BIOLOGICAL RECOGNITION COMPONENTS [J].