miRNAs in colon and rectal cancer: A consensus for their true clinical value

被引：38

作者：

Agostini, Marco ^{[1
]}

Pucciarelli, Salvatore ^{[1
]}

Calore, Federica ^{[1
]}

Bedin, Chiara ^{[1
]}

Enzo, MariaVittoria ^{[1
]}

Nitti, Donato ^{[1
]}

机构：

[1] Univ Padua, Dipartimento Sci Oncol & Chirurg, Clin Chirurg 2, I-35128 Padua, Italy

来源：

CLINICA CHIMICA ACTA | 2010年 / 411卷 / 17-18期

关键词：

microRNAs; Colorectal cancer; B-CELL LYMPHOMAS; COLORECTAL-CANCER; MICRO-RNAS; EXPRESSION; IDENTIFICATION; ACCUMULATION; METASTASIS; SUPPRESSOR; SURVIVAL; MIR-155;

D O I：

10.1016/j.cca.2010.05.002

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Numerous miRNAs are deregulated in human cancers and experimental evidence indicates that they can play roles as oncogenes or tumor suppressor genes. Colorectal cancer represents a wide and exciting area of research for molecular biology, due to the growing need of a molecular classification as well as prognostic and predictive molecilar factors that may guide oncologists in the clinical management of patients. The aim of this review is to analyze the state of art of the miRNA expression profiles in colorectal cancer to explore some perspectives in this research field. (C) 2010 Published by Elsevier B.V.

引用

页码：1181 / 1186

页数：6

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