Selective racemisation of esters: Relevance to enzymatic hydrolysis reactions

被引：11

作者：

Dinh, PM

Williams, JHJ

Harris, W

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] Roche Discovery Welwyn, Welwyn Garden City AL7 3AY, Herts, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(98)02362-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The selective racemisation of an ester in the presence of the corresponding acid has been demonstrated. Phenyl esters are significantly more prone to racemisation than methyl esters. Preliminary results indicate the utility of these results in enzyme-catalysed hydrolysis reactions. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：749 / 752

页数：4

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