Catalytic racemisation of alcohols: Applications to enzymatic resolution reactions

被引：202

作者：

Dinh, PM

Howarth, JA

Hudnott, AR

Williams, JMJ

Harris, W

机构：

[1] UNIV LOUGHBOROUGH,DEPT CHEM,LOUGHBOROUGH LE11 3TU,LEICS,ENGLAND

[2] ROCHE RES CTR,WELWYN GARDEN CIT AL7 3AY,HERTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 42期

基金：

英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/0040-4039(96)01677-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The racemisation of enantiomerically enriched alcohols has been achieved using a catalyst in the presence of a suitable ketone. Aluminium, medium or iridium catalysts have been successfully employed. This methodology allows recycling of substrate for enzymatic resolution reactions. Copyright (C) 1996 Elsevier Science Ltd

引用

收藏

页码：7623 / 7626

页数：4

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