Highly efficient new catalysts for enantioselective transfer hydrogenation of ketones

被引：131

作者：

Langer, T ^{[1
]}

Helmchen, G ^{[1
]}

机构：

[1] UNIV HEIDELBERG,INST ORGAN CHEM,D-69120 HEIDELBERG,GERMANY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 09期

关键词：

D O I：

10.1016/0040-4039(96)00011-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Transfer hydrogenations of alkyl aryl ketones as well as a representative dialkyl ketone with isopropanol catalyzed by Ru complexes of chiral phosphinooxazolines were found to proceed with excellent turnover at a substrate/catalyst mole ratio of 1000:1 to yield products with up to 94% enantiomenic excess.

引用

页码：1381 / 1384

页数：4

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