A significantly improved condition for cyclization of phenethylcarbamates to N-alkylated 3,4-dihydroisoquinolones

被引：47

作者：

Wang, XJ ^{[1
]}

Tan, J ^{[1
]}

Grozinger, K ^{[1
]}

机构：

[1] Boehringer Ingelheim Pharmaceut Inc, Dept Chem Dev, Ridgefield, CT 06877 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(98)01395-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Secondary phenethyl carbamates undergo a Bischler-Napieralski cyclization promoted by phosphorus pentoxide in refluxing phosphorus oxychloride to afford N-alkylated 3,4-dihydroisoquinolones in high yields. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6609 / 6612

页数：4

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