Preparation of fish gelatin and fish gelatin/poly(L-lactide) nanofibers by electrospinning

被引：73

作者：

An Kejing ^{[1
,2
]}

Liu Haiying ^{[1
,2
]}

Guo Shidong ^{[1
]}

Kumar, D. N. T. ^{[3
]}

Wang Qingqing ^{[3
]}

机构：

[1] Jiangnan Univ, Sch Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China

[2] Jiangnan Univ, Natl Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China

[3] Jiangnan Univ, Minist Educ, Key Lab Ecotext, Wuxi 214122, Jiangsu Prov, Peoples R China

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2010年 / 47卷 / 03期

关键词：

Channel catfish gelatin; Electrospinning; Poly(L-lactide); SCAFFOLD; ACID); EXTRACTION; MEMBRANE; COLLAGEN; FIBERS; BLEND; SKINS;

D O I：

10.1016/j.ijbiomac.2010.06.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Ultrafine fibers were successfully fabricated from Channel catfish skin-extracted gelatin via electrospinning (ES). Important ES parameters, such as concentration of aqueous acid and fish gelatin solutions, and electric field intensity were examined to investigate the effects on the morphology of the gelatin nanofibers. Due to the poor mechanical properties of the fish gelatin membranes, composite nanofibers made of fish gelatin and poly(L-lactide)(PLLA) were produced with a novel solution. The introduction of PLLA remarkably improved the mechanical properties of the gelatin membranes. With a combination of good biocompatibility and mechanical properties, fish gelatin/PLLA blending non-woven mats are considered to be very promising in tissue regeneration area. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：380 / 388

页数：9

共 29 条

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