Highly efficient Heck reactions of aryl bromides with n-butyl acrylate mediated by a palladium/phosphine-imidazolium salt system

被引：282

作者：

Yang, CL ^{[1
]}

Lee, HM ^{[1
]}

Nolan, SP ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 10期

关键词：

D O I：

10.1021/ol015827s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new phosphine-imidazolium salt, L.HBr (1 . HBR = (1-ethylenediphenylphosphino-3-(mesityl))imidazol-2-ylidene), has been prepared, A combination of 0.5 mol % of Pd(dba)(2) and 0.5 mol % of L . HBr in the presence of 2 equiv of Cs2CO3 as base has proven to be highly efficient in the Heck coupling reactions of aryl bromides (from electron deficient to electron-rich aryl bromides) with n-butyl acrylate.

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页码：1511 / 1514

页数：4

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