Gold(I)-catalyzed rearrangement of propargylic alcohols to α,β-unsaturated ketones

被引：53

作者：

Lee, Sang Ick

Back, Ji Young

Sim, So Hee

Chung, Young Keun ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Nat Sci, Intelligent Text Syst Res Ctr, Seoul 151747, South Korea

[2] Seoul Natl Univ, Coll Nat Sci, Dept Chem, Seoul 151747, South Korea

来源：

SYNTHESIS-STUTTGART | 2007年 / 14期

关键词：

gold; Meyer-Schuster; rearrangement; alpha; beta-unsaturated ketones; propargylic alcohol;

D O I：

10.1055/s-2007-983725

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have developed a gold(I)-catalyzed rearrangement of propargylic alcohols to a,alpha-beta-unsaturated ketones. The reaction might proceed through a dehydration of an alkynol, followed by an addition of water to a cumulene intermediate. The substituents of the alkynol play an important role in the rearrangement.

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收藏

页码：2107 / 2114

页数：8

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