Whether in catalysis, biology or the protection of the environment, fluorinated functional materials are emerging as important chemical tools to achieve improved performance and higher stability under a variety of conditions. Providing a distinct increase in molecular hydrophobicity, fluorination allows easy tuning of a material's hydrophilic - lipophilic balance (HLB), in particular with sol - gel materials obtained by polycondensation of fluorinated precursors. Reporting on recent remarkable achievements, this review attempts to show the large unexplored potential of these materials.