Recent advances of laser-spectroscopy-based techniques for applications in breath analysis

被引：176

作者：

McCurdy, Matthew R. ^{[1
,2
]}

Bakhirkin, Yury ^{[1
]}

Wysocki, Gerard ^{[1
]}

Lewicki, Rafal ^{[1
]}

Tittel, Frank K. ^{[1
]}

机构：

[1] Rice Univ, Rice Quantum Inst, Houston, TX 77005 USA

[2] Baylor Coll Med, Med Scientist Training Program, Houston, TX 77030 USA

来源：

JOURNAL OF BREATH RESEARCH | 2007年 / 1卷 / 01期

基金：

美国国家科学基金会; 美国国家航空航天局;

关键词：

D O I：

10.1088/1752-7155/1/1/014001

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Laser absorption spectroscopy (LAS) in the mid-infrared region offers a promising new effective technique for the quantitative analysis of trace gases in human breath. LAS enables sensitive, selective detection, quantification and monitoring in real time, of gases present in breath. This review summarizes some of the recent advances in LAS based on semiconductor lasers and optical detection techniques for clinically relevant exhaled gas analysis in breath, specifically such molecular biomarkers as nitric oxide, ammonia, carbon monoxide, ethane, carbonyl sulfide, formaldehyde and acetone.

引用

页数：12

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