Gaucher's disease with Parkinson's disease - Clinical and pathological aspects

被引：107

作者：

Bembi, B

Marsala, SZ

Sidransky, E

Ciana, G

Carrozzi, M

Zorzon, M

Martini, C

Gioulis, M

Pittis, MG

Capus, L

机构：

[1] IRCCS Burlo Garofolo, Unita Operat Dipartimentale Malattie Metab, I-34137 Trieste, Italy

[2] IRCCS Burlo Garofolo, Unita Operat Neuropsichiatria Infantile, I-34137 Trieste, Italy

[3] Univ Trieste, Dipartimento Med Clin & Neurol, I-34127 Trieste, Italy

[4] NIMH, Clin Neurosci Branch, Bethesda, MD 20892 USA

来源：

NEUROLOGY | 2003年 / 61卷 / 01期

关键词：

D O I：

10.1212/01.WNL.0000072482.70963.D7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The association between type 1 Gaucher disease and PD has been reported in the literature. The clinical picture is characterized by the predominance of bilateral akinetic-rigid signs and poor response to levodopa therapy. The authors describe four patients (two siblings) with type 1 Gaucher disease presenting with the following signs of typical PD: asymmetric onset of rigidity, resting tremor, bradykinesia, and a favorable response to Parkinson therapies.

引用

页码：99 / 101

页数：3

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