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Mass spectrometry in proteomics

被引：962
作者：
Aebersold, R [1 ]
Goodlett, DR [1 ]
机构：
[1] Inst Syst Biol, Seattle, WA 98105 USA
来源：
CHEMICAL REVIEWS | 2001年 / 101卷 / 02期
关键词：
D O I：
10.1021/cr990076h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Current methods that are the basis for proteome analysis are reviewed. Focus is on mass spectrometric strategies for protein identification from biological matrixes, computational approaches for searching sequence databases, determination of protein expression levels, and characterization of phosphoproteins and phosphopeptides.
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页码：269 / 295
页数：27
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