Dynamics of transcription and mRNA export

被引：40

作者：

Darzacq, X

Singer, RH

Shav-Tal, Y

机构：

[1] Albert Einstein Coll Med, Dept Anat & Struct Biol, Bronx, NY 10461 USA

[2] Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY 10461 USA

[3] Ecole Normale Super, CNRS, UMR 8541, F-75230 Paris, France

来源：

CURRENT OPINION IN CELL BIOLOGY | 2005年 / 17卷 / 03期

关键词：

D O I：

10.1016/j.ceb.2005.04.004

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Understanding the different molecular mechanisms responsible for gene expression has been a central interest of molecular biologists for several decades. Transcription, the initial step of gene expression, consists of converting the genetic code into a dynamic messenger RNA that will specify a required cellular function following translocation to the cytoplasm and translation. We now possess an in-depth understanding of the mechanism and regulations of transcription. By contrast, an understanding of the dynamics of an individual gene's expression in real time is just beginning to emerge following recent technological developments.

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页码：332 / 339

页数：8

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