XIAP, the guardian angel

被引：233

作者：

Holcik, M

Korneluk, RG

机构：

[1] Childrens Hosp Eastern Ontario, Res Inst, Ottawa, ON K1H 8L1, Canada

[2] AEgera Oncol Inc, Ottawa, ON K1H 8L1, Canada

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 07期

关键词：

D O I：

10.1038/35080103

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Controlling the activity of caspases is essential for the appropriate execution of cell death and the regulation of cell survival, One cellular inhibitor of apoptosis, XIAP, has emerged as a crucial regulator of caspases, and is itself subject to complex negative regulation.

引用

收藏

页码：550 / 556

页数：7

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