Solid phase synthesis of 3-toluenesulfonylglutarimides

被引：2

作者：

Chang, MY ^{[1
]}

Lin, KG

Chen, ST

Chang, NC

机构：

[1] Natl Univ Kaohsiung, Dept Appl Chem, Kaohsiung 811, Taiwan

[2] Acad Sinica, Inst Biol Chem, Taipei 115, Taiwan

[3] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2003年 / 50卷 / 04期

关键词：

solid-phase reaction; stepwise [3+31 strategy; Rink Amide resin; glutarimides; thalidomide;

D O I：

10.1002/jccs.200300111

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel route for the synthesis of 3-toluenesulfonylglutarimides on a solid support is described. The cyclization step involves stepwise [3+3] strategy of Rink Amide resin bound onto an alpha-toluenesulfonyl group with various alpha,beta-unsaturated esters.

引用

页码：795 / 797

页数：3

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